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Cialis (tadalafil) is a medicine that has the capacity to relax muscles and increase flow of blood to particular points of the body. Sirius is important because it is used for treatment of erectile dysfunction or impotence in men. Adcirca is another brand of tadalafil and it is used for treatment of pulmonary arterial hypertension. The medicine also helps in improving exercise capacity in people. •  The starting dose of Cialis recommended by most of the doctors for use as needed in case of most people is 10 mg. The medicine should be taken before sexual activity.

•  The dose can be increased or decreased. It can be increased to 20 mg or decreased to 5 mg. However, the adjustment depends on individual tolerability and efficacy. The maximum recommended frequency for Cialis is once per day in most patients. •  Cialis for use as needed has to improve any problem in case of erectile function compared to placebo. The effect lasts up to 36 hours after taking the medicine.

So, it is important to remember this point while prescribing Cialis for patients. •  The starting was recommended in this case is 2. 5 mg. The medicine should be used at approximately the same time every day. Use of medicine doesn't have anything to do with the timing of sexual activity. •  The Cialis dose for once daily use can be increased to 5 mg.

However, the increment will depend on individual efficacy and tolerability. There is no hard and fast rule for using Cialis with or without food. •  Mild (creatinine clearance 51 to 80 mL/min): do not have to adjust the dose. •  Moderate (creatinine clearance 31 to 50 mL/min): the initial dose is 5 mg to be taken not more than once per day. The maximum dose is restricted to 10 mg to be taken not more than once in every 48 hours. •  Severe (creatinine clearance <30 mL/min and on hemodialysis): The maximum recommended dose in this case is 5 mg.

The medicine should be taken not more than once in every 72 hours •  Mild (creatinine clearance 51 to 80 mL/min): do not have to adjust the dose. •  Moderate (creatinine clearance 31 to 50 mL/min): do not have to adjust the dose. •  Severe (creatinine clearance <30 mL/min and on hemodialysis): not recommended in this case. •  Mild or moderate (Child Pugh Class A or B): the recommended dose of Cialis should be restricted to 10 mg once per day. The use of Cialis once per day should be done very carefully in case of people suffering from hepatic insufficiency because extensive study has not been done in this case. •  Severe (Child Pugh Class C): Cialis is not recommended •  Mild or moderate (Child Pugh Class A or B): Cialis for once daily use should be done very carefully in case of people suffering from hepatic insufficiency because extensive study has not been done in this case.

•  Severe (Child Pugh Class C): Cialis is not recommended. you do not need any dose adjustment for people who are >65 years of age.

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